DeneB Treatment

Technical is Everything


Everything we do is with the integrity of our formulas at top of mind. That means 

we only put out products with ingredients that have been researched, tested, and clinically proven or studied.




More natural, safer, and more effective

Learn about innovative benefits

* This product is a medical device. Please read the instructions for use and precautions carefully before use.

*This image is for illustrative purposes only.

What can you treat with the DeneB®?



DeneB allows for smooth and continuous injections, adapting to both natural procedures and those requiring robust volume enhancement. DeneB provides superior support and volume in the injection area due to its high elasticity. 

What will your patients experience?



Based on rheology, DeneB provides natural results tailored to the treatment area and purpose. DeneB is a unique filler designed with MDM technology to safely and effectively create the beautiful contours desired by patients. 

What are the main advantages for your practice?


DeneB’s hyaluronic acid perfectly implements a granulated particle structure, improving upon the porous structure found in BDDE fillers and ensuring effectiveness and safety.

How Does DeneB® Work?

Unmatched Longevity in Volume and Elasticity


Exhibits the soft properties of Monophasic during injection but stabilizes into Biphasic form for contour corrections. DeneB®’s MDM®-based DVS cross-linking technology creates a compact and highly refined hyaluronic acid structure with molecular chains approximately one-third shorter than those in conventional BDDE cross-linking. This unique structure enhances reactivity upon injection, enabling faster gelation and the creation of a perfect, strong hydrogel.

DeneB® fillers are ideal for anyone looking to enhance their facial contours, correct asymmetries, or achieve a more youthful and balanced appearance. A consultation with a certified practitioner will help determine if MDM®  fillers are right for you. *This product is a medical device. Please read the instructions for use and precautions carefully before use.

DeneB® filler series is CE approved. BioPlus' MDM® filler is known as a global derma filler through numerous clinical studies for its stability and excellence.

You will see results immediatedly. Results are immediately available. Re-touch may be required depending on the patient's infusion dose. Be sure to choose the treatment method based on the diagnosis by the professional medical staff. 

DeneB®’s hyaluronic acid perfectly implements a granulated particle structure, improving upon the porous structure found in BDDE fillers and ensuring effectiveness and safety. DeneB®’s MDM®-applied hyaluronic acid maintains the same spectrum as traditional HA, ensuring safety without altering the high-purity HA properties. 

DeneB® by BioPlus offers a range of products tailored to different treatment purposes and areas, from larger augmentation to fine correction, delivering optimal contours. DeneB® consists of two product lines, creating natural volume for various areas of concern. DeneB® is clinically proven to temporarily improve facial wrinkles in adults. Decisions regarding specific treatment areas and product use should always be made by qualified healthcare professionals.

DeneB® is a top-tier hyaluronic acid filler featuring MDM® technology from the global biomedical company BioPlus. DeneB® combines the high viscosity of Monophasic and the high elasticity of Biphasic fillers, created with high-molecular-weight raw materials of 1.8 million Da and a high cross-linking rate of 1.0~2.0%.


CLINICAL CASES

Incredible changes in filler procedures brought by MDM technology


*Before and after photos may be a compilation of results from all generations of MDM Fillers including DeneB, Hyaldew and Skinplus-Hyal. 

*Unretouched photos. Individual results may vary.